Keira Knightley is set to play the role of a suspected lesbian in a reworking of Lillian Hellman's The Children's Hour, the New York Post reported.

The play, written in 1934, tells the story of two female teachers at a girl's boarding school whose lives are ruined when one of their students accuses the pair of engaging in a lesbian relationship.

The Children's Hour will debut in London's West End next year and possibly move on to Broadway next winter.

Rosie O'Donnell, who is openly gay, might play the part of Knightley's suspected lesbian lover, the Post is reporting.

The 25-year-old, English-born Knightley is best known for starring opposite Johnny Depp in the blockbuster movie franchise the Pirates of the Caribbean.

Ian Rickson, whose Broadway revival of The Seagull earned him great critical praise, will direct the play.

After being banned in Boston, The Children's Hour debuted on Broadway in 1936. A film adaptation of the play starring Shirley MacLaine and Audrey Hepburn was released in 1961.