Premium cable network HBO on Sunday released the first trailer for the upcoming film adaptation of The Normal Heart, Larry Kramer's Tony-winning AIDS play.

HBO will premiere the film on Sunday, May 25.

The film's all-star cast includes Mark Ruffalo, Matt Bomer, Taylor Kitsch, Jim Parsons and Julia Roberts.

Ryan Murphy (Glee, Eat Pray Love) directed the feature length film, which is based on a script written by Larry Kramer (Women in Love).

Ruffalo – a co-star of the 2010 lesbian moms flick The Kids Are Alright – will tackle his first gay role playing Ned Weeks, the hero of Kramer's play about the early days of the AIDS pandemic in New York City.

“We have to do something,” Ruffalo's Weeks is seen saying in the clip. “Nobody else will.”

In another shot, an emotional Weeks screams: “I am trying to understand why nobody gives a shit that we're dying!” (The video is embedded on this page. Visit our video library for more videos.)