John Irving's 13th novel In One Person features two transgender heroes and a bisexual narrator.

“You make all these sexual extremes seem normal – that's what you do and then you expect us to sympathize with them,” the son of a high-school friend tells novelist Billy Abbott in the book.

“Yes,” Abbott replies, “that's more or less what I do.”

In the novel, Abbott falls in love with an older transgender woman, Miss. Frost, and later saves a young transgender student.

There are also devastating chapters set during the 1980s grappling with the AIDS crisis and death. USA Today called those passages “Irving at his best.”

Appearing on The CBS Morning Show to pitch In One Person, Irving said the novel was “pretty much fully formed 10 years ago, 12 years ago and I didn't begin writing it until June of 2009.”

“It's a novel about our lingering, still with us, intolerance for sexual differences,” Irving said. “I chose the bisexual main character because I knew he would generate more distrust from straights and gays alike. He is a deliberately chosen sexual outsider or misfit. And perhaps a part of his attraction to these 2 transgender women of different generations is that he recognizes that they are even more marginalized in society or even more distrusted than he is.”

Writing on, Irving said that the two transgender characters are the heroes of the novel because they are the people Abbott most admires.