Comic Chelsea Handler has told Rick Santorum, Mitt Romney and Newt Gingrich to go “F” themselves, gay entertainment blog reported.

While emceeing a Human Rights Campaign (HRC) fundraiser in Los Angeles on Saturday, Handler, the host of cabler E!'s late night chat show Chelsea Lately, told attendees that she has little respect for the leading GOP presidential candidates.

“There are a lot of people out there who are fighting against what we so strongly believe is a basic human right and three of these people are currently running for the Republican nomination for president – and one of them has been married three times. So obviously he knows what he's talking about,” Handler, 37, said during her opening monologue.

“If it were up to these guys and their supporters, contraception would be banned, 'Don't Ask Don't Tell' would be re-instated and we'd all be sitting in front of our black and white TVs watching Lucy and Desi sleep in separate beds. And that's why I say that these people can go fuck themselves!”