Julia Roberts, Jim Parsons, Alec Baldwin, Matt Bomer and Mark Ruffalo are set to star in the upcoming big screen adaptation of The Normal Heart.

As previously reported, Ruffalo – a co-star of the 2010 lesbian moms flick The Kids Are Alright – will tackle his first gay role playing Ned Weeks, the hero of Larry Kramer's Tony-winning play about the early days of the AIDS crisis.

According to The Hollywood Reporter, Director Ryan Murphy, the creator of Fox's Glee and FX's American Horror Story, has cast Roberts as Dr. Emma Brookner, the only doctor in New York City taking the disease seriously, and Baldwin as Ben Weeks, a lawyer and Ned Weeks' brother. Big Bang Theory co-star Parsons will reprise his Broadway role of AIDS activist Tommy Boatwright.

White Collar star Matt Bomer will also play gay in the film, taking on the role of gay fashion journalist Felix Turner, who later becomes Weeks' boyfriend.

In discussing the role last year with gay glossy The Advocate, Ruffalo said he hesitated before accepting the role.

“It's a great honor, but I was hesitant about doing Normal Heart because it probably should be a gay actor,” Ruffalo said. “I brought that up to Ryan, but he said that I was the actor he wanted.”

Last year, Ruffalo and his wife Sunrise recorded a video in support of New York becoming the sixth state to legalize marriage equality.